Yuyan Han
Associate Professor
School of Biological Sciences
Natural and Health Sciences
Contact Information
Office
Ross Hall, Room 2570
Mailing Address
University of Northern Colorado
School of Biological Sciences
Campus Box
Greeley, CO 80639
Education
Postdoctoral Fellow: Cancer genetics, MD Anderson Cancer Center, Houston TX
PhD.: Medical Science, Texas A&M University, TX
M.S.: Biomedical Engineering, Tongji University, Shanghai, China
B.S.: Biotechnology, Tongji University, Shanghai, China
Professional/Academic Experience
Postdoctoral Fellow,
MD Anderson Cancer Center, Houston, TX, 2015-2018
Biology instructor(Adjunct),
Houston Community College, TX, 2015-present
Assistant Research Scientist,
Texas A&M University, Temple, TX, 2014-2015
Classes taught
Research/Areas of Interest
My research interests are in the areas of non-alchoholic fatty liver disease (NAFLD),
obesity, circadian rhythm, epigenetics and cancer biology.
Publications/Creative Works
- Han Y, Junfeng Xu, Jeri Kim, Xifeng Wu, Jian Gu; Methylation of subtelomeric repeat D4Z4
in peripheral blood leukocytes is associated with biochemical recurrence in localized
prostate cancer patients, Carcinogenesis. 2017 Aug; 38 (8) : 821–826, doi: 10.1093/carcin/bgx064. PMID: 28854562
- Han Y, Junfeng Xu, Jeri Kim, Xifeng Wu, Jian Gu; LINE-1 methylation in peripheral blood leukocytes
and clinical characteristics and prognosis of prostate cancer patients, Oncotarget. 2017 Oct; 8:94020-9402, doi: 10.18632/oncotarget.21511
- Han Y, Demorrow S, Invernizzi P, Jing Q, Glaser S, Renzi A, Meng F, Venter J, Bernuzzi
F, White M, Francis H, Lleo A, Marzioni M, Onori P, Alvaro D, Torzilli G, Gaudio E,
Alpini G. Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma:
its synthesis is reduced favoring cholangiocarcinoma growth. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G623-33. doi: 10.1152/ajpgi.00118.2011. PMID: 21778461
- Han Y, Glaser S, Meng F, Francis H, Marzioni M, McDaniel K, Alvaro D, Venter J, Carpino G, Onori P, Gaudio
E, Alpini G, Franchitto A. Recent advances in the morphological and functional heterogeneity
of the biliary epithelium. Exp Biol Med (Maywood). 2013 May;238(5):549-65. doi: 10.1177/1535370213489926. Review. PMID: 23856906
- Han Y, Onori P, Meng F, DeMorrow S, Venter J, Francis H, Franchitto A, Ray D, Kennedy L,
Greene JF, Renzi A, Mancinelli R, Gaudio E, Glaser S, Alpini G. Prolonged exposure
of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis.
Am J Physiol Gastrointest Liver Physiol. 2014 Sep 11. doi: 10.1039/c4cc04835k. PMID: 25214401
- Han Y*, Francis H*, McDaniel K*, Liu X, Kennedy L, Yang F, McCarra J, Zhou T, Glaser S,
Venter J, Huang L, Levine P, Lai JM, Liu CG, Alpini G, Meng F. Regulation of the extrinsic
apoptotic pathway by microRNA-21 in alcoholic liver injury. J Biol Chem. 2014 Oct 3. doi: 10.1074/jbc.M114.602383. PMID: 25118289 (Equal contribution first-author)
- Han Y, Meng F, Venter J, Wu N, Wan Y, Standeford H, Francis H, Meininger C, Greene J Jr,
Trzeciakowski JP, Ehrlich L, Glaser S, Alpini G. miR-34a-dependent overexpression
of Per1 decreases cholangiocarcinoma growth. J Hepatol. 2016 Jun;64(6):1295-304. doi: 10.1016/j.jhep.2016.02.024. Epub 2016 Feb 24. PMID:
26923637This is the content region for publications and creative works.
Honors and Awards
